- April 14 – The foundation stone of Nantes Cathedral in Nantes, France, is laid.
- May 30 – Hussite Wars – Battle of Lipany: The Catholics and Ultraquists defeat the Taborites, ending the Hussite Wars.
- June 19 or 20 – Zara Yaqob becomes Emperor of Ethiopia.
- Late June – Miner Engelbrekt Engelbrektsson begins a Swedish rebellion against king Eric of Pomerania (named the Engelbrekt rebellion after him), eventually leading to the deposition of the king.
- July 10–August 9 – Suero de Quiñones and his companions stage the Passo Honroso at the Órbigo in León.
- August 16 – King Eric of Pomerania is deposed from the Swedish throne at a meeting in Vadstena. He still retains power in Denmark and Norway, though.
- September – Cosimo de' Medici returns to Florence one year, to the day, following his exile by the Alberti and Strozzi faction.
- October 19 – The University of Catania is founded in Italy.
- Jan van Eyck paints the Arnolfini Portrait.
- Explorer Gil Eanes rounds Cape Bojador in Western Sahara, thus destroying the legends of the "Dark Sea".
- Portuguese traders deliver their first cargo of African slaves to Lisbon.
- In Ming DynastyChina, a long episode of drought, flood, locust infestation, and famine cripple agriculture and commerce in areas throughout the country until 1448.
- January 7 – Adolf, Duke of Bavaria (d. 1441)
- March 12 – William III, Count of Henneberg-Schleusingen (d. 1480)
- March 19 – Ashikaga Yoshikatsu, Japanese shogun (d. 1443)
- March 25 – Eustochia Smeralda Calafato, Italian saint (d. 1485)
- June 13 – Cristoforo della Rovere, Roman Catholic cardinal (d. 1478)
- September 18 – Eleanor of Portugal, Holy Roman Empress (d. 1467)
- September 23 – Yolande of Valois, Duchess consort of Savoy (d. 1478)
- December 28 – Antonio Grimani, Italian admiral (d. 1523)
- May 30
- June 1 – King Wladislaus II of Poland
- June 19 – Alexandra of Lithuania, Duchess of Masovia
- November 12 – King Louis III of Naples (b. 1403)
- date unknown