Karanikolaou was born and raised in California and is of Greek descent. She has been best friends with Kendall and Kylie Jenner since she was 11-years-old. She is also friends with Jordyn Woods, Jaden Smith, and Hailey Baldwin.
Karanikolaou's close proximity to the Kardashian family has helped her garner fame in her own right. On Instagram, she has over 2.1 million followers and on Twitter boasts 189k followers as of November 2016. She has begun a career in modeling.