The Casper Star-Tribune is a newspaper published in Casper, Wyoming.

It is Wyoming's largest print newspaper, with a daily circulation of 23,760 and a Sunday circulation of 21,041.[2] The Star-Tribune covers local and state news. Its website, Trib.com, includes articles from the print paper, online updates, video and other multimedia content.

In 2002, the newspaper was acquired by Lee Enterprises.