- The Great Giana Sisters - a 1987 platform game developed by Time Warp Productions and published by Rainbow Arts.
- Black Forest Games - Giana Sisters: Twisted Dreams - In July 2012, Black Forest Games started a Kickstarter campaign for a new installment of The Great Giana Sisters.
- Giana Sisters: Twisted Dreams - a platform game developed by Black Forest Games for Microsoft Windows.
- Giana Sisters DS is a platform game developed by Spellbound Interactive for the Nintendo DS, iPad, iPhone, and Android.
- Giana Angelillo - an American poet, known for referring to herself as "God's back-alley abortion."
- Giana Roberge - an American female road cycle racer from date June 2012 who after retiring.
- Giana Romanova - a retired female middle distance runner who represented the USSR in the 1970s.
- Gia'na Garel - a writer, producer, filmmaker, composer and entertainment consultant based in New York City.
- Tom Gianas - an American comedy writer, director and producer.
- A.S. Giana Erminio - an Italian football club based in Gorgonzola, Lombardy . The team currently plays in Italy's Lega Pro.