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The Hilton Garden Inn Sioux Falls hotel in South Dakota is located at the intersection of I-229 and Louise Avenue, 15 minutes southwest of Sioux Falls Regional (FSD) Airport and eight blocks from The Empire Mall. Our hotel in Sioux Falls is surrounded by fine restaurants and shopping, and is conveniently located near the Sioux Falls Convention Center, Sioux Falls Arena, Sanford Heath, Avera Mckennan Hospital, the Heart Hospital of South Dakota, Augustana College, University of Sioux Falls and Colorado Technical Institute. Four university campuses are within a half-mile of the hotel. Take the complimentary shuttle to and from Sioux Falls Regional Airport between 5:00am and 11:00pm. Find everything you need for a productive stay in Sioux Falls, SD, including complimentary WiFi and a 24-hour business center. Maintain your fitness on the cardio equipment and weights of our fitness center, and cool off in the indoor pool. The Great American Grill® is open early for breakfast and stays open for evening meals, drinks and networking. Host a Sioux Falls meeting in chic boardrooms, and celebrate with up to 250 guests in the Garden Ballroom. [+]