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The Holiday Inn® Martinsburg hotel's location provides guests with a quiet yet convenient destination that is ideal for every type of traveler. While the area may seem rural and removed, there is plenty of excitement in Martinsburg, WV for the hotel's visitors. Martinsburg, West Virginia gives business travelers an array of opportunities. The hotel is positioned right off of I-81, which allows patrons quick commutes to their professional destinations, including the IRS National Computer Center, VA Medical Center, Essroc, United States Coast Guard OSC Procter & Gamble and University Healthcare - Berkeley Medical Center. [+]