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Welcome to Florida's Treasure Coast, renowned for its sunken Spanish ships, gorgeous, unpopulated beaches and fascinating biological diversity. The Holiday Inn® Port St. Lucie hotel is in the heart of the Treasure Coast, surrounded by picturesque towns, parks and waterways. Stay with us and enjoy all the comforts of home as this hotel's valued guest. In Port St. Lucie, Florida, you can play a round of golf at PGA Village and watch the NY Mets train at Digital Domain Park. Patrons can also visit Fort Pierce, our neighboring town, to tour the A.E. Backus Museum, catch a show at the historic Sunrise Theater and observe manatees at Moore's Creek. Many nearby companies lead daily kayaking, dolphin watching and fishing excursions, as well. [+]