Born in Rivne, Ukraine, Natalya is the daughter of Igor and Jadwiga (née Antonovich) Pasichnyk. Her father became the first rector of National University of Ostroh Academy when it was revived in 1994. Her sister is the soprano Olga Pasichnyk.
Natalya started her musical studies at the age of three. After graduating from the Music Boarding School in Lviv she continued at the Lviv National Musical Academy, M. Lysenko for professor Josef Örmeny. She then finished her postgraduate studies for professor Andrzej Stefański at the in Warsaw and for Staffan Scheja at the Royal Swedish Academy of Music.
Natalya has performed widely, both as soloist and accompanying her sister Olga. She has appeared throughout Europe, USA, and Japan, in concert halls such as Suntory Hall (Tokyo), Berwaldhallen (Stockholm), Konserthuset (Stockholm), de Singel (Antwerp), Auditori Winterthur (Barcelona), Laeiszhalle (Hamburg), and in the major Polish concert halls., at festivals such as Beethoven-festival and Mozart festival, , Gdansk Piano Autumn (Poland), Schubertiada (Spain), Palaces of St. Petersburg (Russia). She cooperated with the Swedish Radio Symphony Orchestra, Mozarteum (Germany), (France), Philharmonic Orchestra of Kraków, Wrocław, Gdańsk and Poznań (Poland), Norrlandsoperan (Sweden) under the direction of such conductors as Christopher Hogwood, Evgeniy Svetlanov, Arie van Beck, Jacek Kaspszyk, Marek Mos, B Tommy Andersson, Robert Stehli. She is prizewinner of the Fifth in Nyborg (Denmark, 1998), and in Cincinnati (USA, 1999).