Slig may refer to any of the following fictional creatures:

  • Slig (Dune), a slug-pig hybrid created by the Bene Tleilax and considered a delicacy, in Frank Herbert's Dune universe
  • A creature in the Oddworld video game universe
  • A creature in the Dragonlance universe of novels and related media
  • An insectoid, tentacled race of creatures encountered by Marvel Comics' Fantastic Four superhero team (see List of Marvel Comics alien races#S)
  • A member of Deep Six (DC Comics), a group of DC Comics villains