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First trained as a physicist, Uri Alon found a passion for biological systems. At the Weizmann Institute of Science in Israel, he and his lab investigate the protein circuits within a cell (they focus on E. coli), looking for basic interaction patterns that recur throughout biological networks. It's a field full of cross-disciplinary thinking habits and interesting problems. And in fact, Alon is the author of a classic paper on lab behaviour called "How to Choose a Good Scientic Problem," which takes a step back from the rush to get grants and publish papers to ask: How can a good lab foster growth and self-motivated research? [+]